MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

SYSTEMIC SCLEROSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What are the minimum criteria for the diagnosis of systemic sclerosis?
A
hardening of the skin on the toes or fingers
B
shapeless ulcers on the tips of the fingers
C
Fingers become shorter due to hardening of the skin
D
2-sided lower lobe hardening of the lungs
E
hardening of the skin involving the toes or fingers and a larger area
Explanation: 

Detailed explanation-1: -Characteristics of systemic sclerosis include essential vasomotor disturbances; fibrosis; subsequent atrophy of the skin (see the image below), subcutaneous tissue, muscles, and internal organs (eg, alimentary tract, lungs, heart, kidney, CNS); and immunologic disturbances accompany these findings.

Detailed explanation-2: -Antinuclear antibody (ANA) testing is the most important blood test to screen for scleroderma and other connective tissue diseases.

There is 1 question to complete.