MRCP UK EXAMINATIONS

ABDOMINAL

HEMOGLOBINOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In the mountains some clinically healthy people present with anaemia symptoms. Blood test can reveal sickle cells. What is the genotype of such people?
A
B
C
D
Explanation: 

Detailed explanation-1: -People with Hemoglobin SC disease have red blood cells that are differently shaped and therefore do not carry oxygen as effectively. Symptoms of Hemoglobin SC disease include anemia and episodes of fatigue and extreme pain (vaso-occlusive crisis). The severity of the symptoms can vary from person to person.

Detailed explanation-2: -People who inherit one sickle cell gene and one normal gene have sickle cell trait (SCT). People with SCT usually do not have any of the symptoms of sickle cell disease (SCD), but they can pass the trait on to their children.

There is 1 question to complete.