MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

HYPERTHYROIDISM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A patient reports they consume too much of foods that contain iodine. What condition are they most susceptible to?
A
Type I Diabetes Mellitus
B
Pheochromocytoma
C
Hypothyroidism
D
Hyperthyroidism
Explanation: 

Detailed explanation-1: -[1] Goiter, a lump in the front of the neck from an enlarged inflamed thyroid gland, can result from hypothyroidism, hyperthyroidism, or an excessive iodine intake (usually involves taking very high doses of more than 18, 000 mcg a day for a prolonged time).

Detailed explanation-2: -Iodine induced hyperthyroidism may be dangerous in patients with underlying heart disease. In iodine sufficient individuals, iodine excess causes elevated thyroid-stimulating hormone levels, which inhibits thyroid hormone production leading to hypothyroidism and goiter.

Detailed explanation-3: -In hyperthyroid patients, iodine acutely inhibits hormonal secretion [1], but the responsible mechanisms are uncertain. This is the most acute effect of iodine on thyroid status, occurring within hours of the start of therapy.

There is 1 question to complete.