NEUROLOGY
MOTOR NEURONE DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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There is an increase in concentration of sodium ions inside the neurone.
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The neurone membranes become polarised.
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The Pacinian corpuscle membrane becomes more permeable to sodium ions.
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The stretch-mediated sodium channels narrow.
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Detailed explanation-1: -In corroboration of this supposition, stimulation of Pacinian corpuscle afferent fibers in humans induces a sensation of vibration or tickle. They make up 10–15% of the cutaneous receptors in the hand. Pacinian corpuscles located in interosseous membranes probably detect vibrations transmitted to the skeleton.
Detailed explanation-2: -Pacinian corpuscles are examples of receptors found in the skin. They belong to the family of mechanoreceptors. Pacinian corpuscles respond to the sensation of touch by transducing mechanical pressure into a generator potential, a type of nervous impulse.
Detailed explanation-3: -The Pacinian corpuscle (PC), a cutaneous mechanoreceptor located deep within the dermis of the skin, detects high frequency vibrations that occur within its large receptive field. The PC is comprised of lamellae that surround the nerve fiber at its core.