MRCP UK EXAMINATIONS

Detailed explanation-1: -The most common intrahepatic causes are viral hepatitis, alcoholic cirrhosis, primary biliary cirrhosis, drug induced jaundice, and alcoholic hepatitis. Posthepatic jaundice is most often due to biliary obstruction by a stone in the common bile duct or by carcinoma of the pancreas.

Detailed explanation-2: -Obstructive Jaundice-What it is Yellowing of the skin and whites of the eyes, light-coloured stools and dark urine could be signs of obstructive jaundice – a condition where normal drainage of bile from the liver to the small intestines is blocked.

Detailed explanation-3: -Disruption in the bile flow due to impairment of the intrahepatic biliary system is generally referred to as cholestasis. Cholestasis can present as abnormalities in serum hepatic enzymes, such as elevated bilirubin and alkaline phosphatase levels, and can lead to jaundice and pruritis.