MRCP UK EXAMINATIONS

ABDOMINAL

CHRONIC LIVER DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What do Kupffer cells produce?
A
bile
B
bile pigments
C
amino acids
D
urea
Explanation: 

Detailed explanation-1: -Kupffer cells are resident liver macrophages and play a critical role in maintaining liver functions. Under physiological conditions, they are the first innate immune cells and protect the liver from bacterial infections.

Detailed explanation-2: -Examples of endogenous hematogenous pigments found in the liver are hemosiderin and bilirubin. Examples of endogenous nonhematogenous pigments found in the liver are lipofuscin (fatlike) and copper (non-fatlike). Fetal liver tissue will always demonstrate endogenous nonhematogenous copper pigment.

Detailed explanation-3: -Kupffer cells (also known as stellate sinusoidal macrophages or Kupffer-Browicz cells) are macrophages found in the sinusoids of the liver.

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