MRCP UK EXAMINATIONS

Detailed explanation-1: -Excessive alcohol consumption is a risk factor for cirrhosis. Being overweight. Being obese increases your risk of conditions that may lead to cirrhosis, such as nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Having viral hepatitis.

Detailed explanation-2: -Obesity also plays a detrimental role in the progression of liver disease to cirrhosis. In patients with NAFLD obesity is independently associated with the presence of hepatic inflammation and fibrosis (non-alcoholic steato-hepatitis, NASH) and with an increased risk of progression to cirrhosis.

Detailed explanation-3: -Infection, especially SBP, is the commonest precipitating factors of HE followed by electrolyte imbalance, constipation, and GIB.

Detailed explanation-4: -Obesity is associated with an increased risk of nonalcoholic fatty liver disease (NAFLD). Steatosis, the hallmark feature of NAFLD, occurs when the rate of hepatic fatty acid uptake from plasma and de novo fatty acid synthesis is greater than the rate of fatty acid oxidation and export (as triglyceride within VLDL).