MRCP UK EXAMINATIONS

ABDOMINAL

CHRONIC LIVER DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the name of the cycle that converts ammonia into urea for excretion?
A
arginine
B
ornithine
C
citrulline
D
uric acid
Explanation: 

Detailed explanation-1: -The urea cycle or ornithine cycle converts excess ammonia into urea in the mitochondria of liver cells.

Detailed explanation-2: -Argininosuccinate undergoes cleavage by argininosuccinase to form arginine and fumarate. Arginine is cleaved by arginase to form urea and ornithine. The ornithine is then transported back to the mitochondria to begin the urea cycle again.

Detailed explanation-3: -Ornithine cycle occurs in liver. In ornithine cycle, urea is produced from ammonia.

There is 1 question to complete.