MRCP UK EXAMINATIONS

ABDOMINAL

CHRONIC LIVER DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the name of the enzyme that breaks down alcohol?
A
ethanal dehydrogenase
B
ethanoate dehydrogenase
C
ethanol
D
ethanol dehydrogenase
Explanation: 

Detailed explanation-1: -Most of the ethanol in the body is broken down in the liver by an enzyme called alcohol dehydrogenase (ADH), which transforms ethanol into a toxic compound called acetaldehyde (CH3CHO), a known carcinogen.

Detailed explanation-2: -Alcohol metabolism is controlled by genetic factors, such as variations in the enzymes that break down alcohol, and environmental factors, such as the amount of alcohol an individual consumes and his or her overall nutrition.

Detailed explanation-3: -The zinc containing, well-known liver enzyme is a class I medium-chain alcohol dehydrogenase. Other classes of this family include the class II protein, the glutathione-dependent formaldehyde dehydrogenase (the class III enzyme), the stomach-expressed class IV form, and the recently defined class V protein.

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