MRCP UK EXAMINATIONS

ABDOMINAL

CHRONIC LIVER DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the name of the process in which excess amino acids undergo a conversion in the liver to form urea with the removal of the amino group?
A
absorption
B
assimilation
C
digestion
D
deamination
Explanation: 

Detailed explanation-1: -In the liver, the amino acid is converted to ammonia soluble in water to form alkaline fluid, which is toxic through deamination. This toxic substance is converted to urea for safe excretion.

Detailed explanation-2: -The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). Animals that use this cycle, mainly amphibians and mammals, are called ureotelic.

Detailed explanation-3: -Deamination of amino acids is mainly done by liver (separation of amino group of amino acid and its conversion to ammonia). Preparation of urea from the amino acids is done by the liver. Liver converts ammonia (obtained from deamination) into urea through ornithine cycle.

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