MRCP UK EXAMINATIONS

Detailed explanation-1: -Amino acid degradation or nitrogen metabolism results in the formation of ammonia, excess ammonia are removed as urea by the Urea cycle or Krebs-Henseleit Cycle. Urea is formed in the liver and excreted in the urine. Hence, the end product of nitrogen metabolism in mammals is urea.

Detailed explanation-2: -In oxidative deamination, amino groups are removed from amino acids, resulting in the formation of corresponding keto acids and ammonia.

Detailed explanation-3: -Urea is the chief nitrogenous waste of mammals. Most of our nitrogenous waste comes from the breakdown of amino acids. This occurs by deamination. Deamination of amino acids results in the production of ammonia (NH3).

Detailed explanation-4: -The answer to what is deamination is the breakdown of amino acids into ammonia.