ABDOMINAL
CHRONIC LIVER DISEASE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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when are increased blood levels present? (ALP)
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when cholestasis or bone degeneration is present
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when myleostasis or enzyme synthesis is present
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when lipostasis or bone synthesis is present
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when cholestasis or protein degeneration is present
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Explanation:
Detailed explanation-1: -ALP rises because of the increased synthesis and membrane shedding of ALP from hepatocytes exposed to the increased biliary pressure of cholestasis whereas bilirubin rises due to a failure of bilirubin excretion.
Detailed explanation-2: -People with Paget’s disease of bone often have raised levels of ALP, although some people with the condition have a normal ALP level and a high level can also be caused by some other conditions. An X-ray or scan is therefore also needed to confirm the diagnosis.
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