ABDOMINAL
GASTROINTESTINAL
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Clinical experiment is conducted in which one group of subjects is given 50g of glucose intravenously and another group is given 50 g of glucose orally. Which of the following factors can explain why the oral glucose load is cleared from the blood at a faster rate compared to the intravenous glucose load?
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CCK-induced insulin release
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CCK-induced VIP release
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GIP-induced glucagon release
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GIP-induced insulin release
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Explanation:
Detailed explanation-1: -The Esophageal Phase Both esophageal sphincters, first the upper, and then the lower, open in response to the pressure of the food bolus and close after the food bolus passes.
Detailed explanation-2: -The proximal stomach undergoes mainly receptive relaxation and tonic contraction during the ingestion and digestion of a meal.
Detailed explanation-3: -The presence of fat, such as oleate, in the meal results in stimulation of cholecystokinin (CCK) secretion in the duodenum; in turn, this inhibits antral motility, stimulates pyloric tone and delays gastric emptying [8]. CCK is the first of a repertoire of hormones that regulate gastric emptying.
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