MRCP UK EXAMINATIONS

ABDOMINAL

GASTROINTESTINAL

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What effect would cause some reflexes to block the arrival of new acid content from the stomach until the pancreatic game neutralizes the duodenal chyme.
A
A PH of less than 3.5 to 4
B
A PH of 7
C
A Ph of 7.35 to 7.85
D
None of the above
Explanation: 

Detailed explanation-1: -The enterogastric reflex is stimulated by duodenal distension. It can also be stimulated by a pH of 3-4 in the duodenum and by a pH of 1.5 in the stomach. Upon initiation of the reflex, the release of gastrin by G-cells in the antrum of the stomach is shut off.

Detailed explanation-2: -The secretion is blocked by cholinergic inhibition, suggesting a gastropancreatic vagovagal reflex [117]. When gastric juice and contents of a meal enter the duodenum, a variety of intraluminal stimulants can act on the intestinal mucosa to stimulate pancreatic secretion through both neural and humoral mechanisms.

Detailed explanation-3: -Secretin stimulates the secretion of bicarbonate-rich pancreatic fluid. [11] Secretin enters the intestinal lumen and stimulates bicarbonate secretion, ultimately neutralizing gastric H+, which plays an essential role in fat digestion by creating a more neutral (pH 6 to 8) environment.

Detailed explanation-4: -In order to neutralize the acidic chyme, a hormone called secretin stimulates the pancreas to produce alkaline bicarbonate solution and deliver it to the duodenum.

There is 1 question to complete.