MRCP UK EXAMINATIONS

Detailed explanation-1: -In small human islets (40–60 m in diameter), -cells had a core position, -cells had a mantle position, and vessels laid at their periphery. In bigger islets, -cells had a similar mantle position but were found also along vessels that penetrate and branch inside the islets.

Detailed explanation-2: -The islets of Langerhans contain four cell types that each secrete a different peptide: alpha cells secrete glucagon, beta cells secrete insulin, delta cells secrete somatostatin, and P (F) cells secrete pancreatic polypeptide.

Detailed explanation-3: -The normal human pancreas contains about 1 million islets. The islets consist of four distinct cell types, of which three (alpha, beta, and delta cells) produce important hormones; the fourth component (C cells) has no known function.