ABDOMINAL
GASTROINTESTINAL
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Arrival of chyme in the intestine
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CCK secretion
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Motility inhibition
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Decreased insulin secretion
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Detailed explanation-1: -CCK is produced by two separate cell types: endocrine cells of the small intestine and various neurons in the gastrointestinal tract and central nervous system.
Detailed explanation-2: -Cholecystokinin (CCK) is a hormone secreted by the I-cells of the upper small intestine in response to fat, protein, and some nonnutrients, for example, camostat, and a peptide/neurotransmitter secreted by neurons of the central and peripheral nervous systems.
Detailed explanation-3: -CCK receptors signal through the phosphatidyl inositol pathway. This leads to increases in diacylglycerol and intracellular Ca2+. Also, CCK has been shown to increase levels of cyclic guanosine monophosphate (cGMP).
Detailed explanation-4: -In addition to the role of neural pathways, the hormone CCK plays a major role in meal-stimulated digestive enzyme secretion during the intestinal phase.