MRCP UK EXAMINATIONS

ABDOMINAL

GASTROINTESTINAL

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is NOT a direct cause of jaundice?
A
Gallstones
B
Hepatitis
C
Cirrhosis
D
Bladder infections
Explanation: 

Detailed explanation-1: -Urinary tract infections (UTI) are attributed as the main reason for prolonged jaundice, and it is well known that UTI can occur without apparent signs, and jaundice is an important and sometimes the presenting feature of UTI[7].

Detailed explanation-2: -Jaundice can occur in adults when bilirubin is higher than 2.3 mg/dL [37]. The UGT1A1 enzyme, which converts indirect bilirubin into direct bilirubin, is well-developed in the adult liver, but not in the livers of newborns. This is why jaundice with high indirect bilirubin is common in babies [2].

Detailed explanation-3: -Anemia leads to increased excretion of bilirubin in the blood and subsequent decrease in the number of RBC’s. Abnormal secretion of pancreatic and gastric juices has nothing to do with bilirubin levels thus are not the symptoms found in jaundice patients.

There is 1 question to complete.