ABDOMINAL
GENERALISED LYMPHADENOPATHY
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Question
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A 47-year-old man died of an acute anemia, resulted from the pulmonary bleeding. An autopsy revealed in the 2 segment of the right lung the cavity, 5-6 cm in the size, which had connection with the bronchus lumen. The cavity had irregular roundish form and filled with blood. The internal surface of a cavity was rough and covered by a flabby unstructured yellowish tissue. A wall was thin, presented by the condensed, inflammatorily changed pulmonary tissue A histological investigation showed that the cavity inside layer consisted of the fused caseous masses with a considerable quantity of segmented leucocytes. What is the most likely pathology presented in that case?
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Acute cavernous tuberculosis
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Abscess of lung
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Disintegrating carcinoma of lung
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Infarction of lung with septic disintegration
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Explanation:
Detailed explanation-1: -Microscopically, the inflammation produced with TB infection is granulomatous, with epithelioid macrophages and Langhans giant cells along with lymphocytes, plasma cells, maybe a few neutrophils (PMN’s), fibroblasts with collagen, and characteristic caseous necrosis in the center.
Detailed explanation-2: -MORPHOLOGY OF SECONDARY TB Initial lesion is usually a small area of consolidation at the lung apex. Progressive pulmonary TB, common in elderly or immunocompromised, occurs as an expansion of apical lesion (Fig IV) with expansion of area of caseation erosion into bronchus evacuates the caseous center leaving a cavity.
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