MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A 52-year-old man with a history of hematogenic tuberculosis presented to the hospital with hyperpigmentation skins (melanosis) and mucosas, a cachexia, cardiovascular insufficiency. What disease caused such changes?
A
Addison’s disease
B
Pheochromocytoma
C
Simmonds’ disease
D
Itsenko-Cushing disease
Explanation: 

Detailed explanation-1: -Addison disease is classically seen with hyperpigmentation due to ACTH melanogenesis. Intraorally pigmentation over the gingival, vermillion border of lip, buccal mucosa, palate tongue, is evident and perceived as first sign.

Detailed explanation-2: -Tuberculosis (TB) is the most common cause of Addison’s disease worldwide, but is rare in the UK. TB is a bacterial infection that mostly affects the lungs, but can also spread to other parts of your body. It can cause Addison’s disease if it damages your adrenal glands.

There is 1 question to complete.