ABDOMINAL
GENERALISED LYMPHADENOPATHY
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
A 56-year-old woman with a long history of parathyroid glands disease, died from increased renal insufficiency. A post-mortem revealed a bones deformation of extremities, a vertebral column, and ribs. Bones were fragile, soft and easily deformed or cat. They had some motley tumorous formations. Kidneys were contracted. Histological investigation revealed lacunar bone resorption. In addition, a microscopic study demonstrated giant cell granulomas within the centres of tumorous formations, accumulations of erythrocytes and a hemosiderin. Name the described disease.
|
|
Parathyroid osteodystrophy
|
|
|
Metastases of cancer in a bone
|
|
|
Chronic renal insufficiency
|
|
|
Paget’s disease
|
Explanation:
Detailed explanation-1: -Excess parathyroid hormone can lead to negative effects on the body such as osteoporosis which can lead to fractures, kidney stones, decreased kidney function, heart disease, pancreatitis, increased acid secretion in the stomach and ulcers.
Detailed explanation-2: -Parathyroid hormone is mainly controlled by the negative feedback of calcium levels in the blood to the parathyroid glands. Low calcium levels in the blood stimulate parathyroid hormone secretion, whereas high calcium levels in the blood prevent the release of parathyroid hormone.
There is 1 question to complete.