MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A 56 years old patient has moderate icterus of skin and scleras, enlargement of liver and spleen. 3 years ago he was treated for hepatitis B. The examination detected:HBsAg, HBeAg (+), the high concentration of HBV DNA. Which drug is the most suitable for basic treatment of the illness?
A
Vitogepat
B
Essentiale forte
C
Alpha-interferon
D
Carsil
E
Prednisolone
Explanation: 

Detailed explanation-1: -Hepatitis B surface antigen (HBsAg) is the first serum marker seen in persons with acute infection.

Detailed explanation-2: -A positive HBeAg indicates high levels of virus in the blood and a person is considered infectious. A negative HBeAg indicates very low to no virus in the blood and a person is usually considered less infectious; sometimes this can indicate a person has a mutant hepatitis B virus (see below).

Detailed explanation-3: -Hepatitis B surface antibody (anti-HBs): The presence of anti-HBs is generally interpreted as indicating recovery and immunity from hepatitis B virus infection. Anti-HBs also develops in a person who has been successfully vaccinated against hepatitis B.

Detailed explanation-4: -Infants born to HBsAg-positive mothers should receive HBIG (0.5 mL) intramuscularly (IM) once they are physiologically stable, preferably within 12 hours after birth. HB vaccine, either plasma-derived (10 *gmg per dose) or recombinant (5 *gmg per dose), should be administered IM in three doses of 0.5 mL each.

There is 1 question to complete.