ABDOMINAL
GENERALISED LYMPHADENOPATHY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A 63-years-old patient, with a history of hypertensive disease, died from cardiac insufficiency. At autopsy, the heart enlargement and dilated ventricular cavities were revealed. Microscopical investigation showed marked hypertrophy of cardiomyocytes, with their fatty dystrophy and hyperchrotnic barrel-like nucleuses. What pathological process is the most likely in a heart?
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Eccentric hypertrophy
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Myocarditis
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Concentric hypertrophy
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Angiogenic cardiosclerosis
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Explanation:
Detailed explanation-1: -When the aortic or mitral valves are leaking, the left ventricle adapts to the increased volume load by getting larger. This results in cardiomegaly. If the aortic valve is narrow, this results in an obstruction to the left ventricle which develops hypertrophy and cardiomegaly.
Detailed explanation-2: -Heart failure developing after MI hospitalization is a consequence of cardiomyocyte death and scar formation, which triggers chronic neurohumoral activation (renin–angiotensin–aldosterone and sympathetic nervous system up-regulation) and ventricular remodelling.
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