A 7-year-old boy with a history of tonsillitis presented with markedly enlarged paratracheal, bifurcate and cervical lymph nodes. A microscopical investigation of the removed cervical lymph node revealed the centers of a necrosis surrounded with lymphocytes, epithelioid cells and Pirogov-Langhans cells. Specify the most likely pathology.

GENERALISED LYMPHADENOPATHY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A	Tuberculosis
B	Sarcoidosis (Boeck’s disease)
C	Rhinoscleroma.
D	Glanders

Explanation:

Detailed explanation-1: -The symptomatology is acute with fever and painful, erythematous lumps over the neck. Tuberculous cervical lymphadenitis (also known as scrofula) is caused by Mycobacterium tuberculosis and presents with malaise, weight loss, and nontender neck lumps.

Detailed explanation-2: -Cervical tuberculosis is usually a result of an infection in the lymph nodes, known as lymphadenitis. Extrapulmonary tuberculosis, such as scrofula, is observed most often in individuals who are immunocompromised.

Detailed explanation-3: -In differential diagnosis of CTL, other granulomatous lymphadenitis should be considered such as non-tuberculous mycobacteria (including M. scrofulaceum, M. avium, and M. haemophilum), sarcoidosis, toxoplasmosis, tularemia, fungal disease, cat-scratch disease and neoplasms [7, 8].

There is 1 question to complete.

MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY