MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A histological investigation of a thyroid gland, presented to pathology, revealed a mild atrophy of a parenchyma, sclerosis, diffusive infiltration of a stroma by lymphocytes and plasmocytes with formation of lymphoid follicles. What is the most likely diagnose?
A
Autoimmune thyroiditis
B
Parenchymatous goiter
C
Toxic goiter
D
Thyroiditis
Explanation: 

Detailed explanation-1: -Thyroid atrophy is the end result of either severe thyroid damage or total loss of pituitary stimulation. The possible causes are: (1) irradiation (2) atrophic auto-immune thyroiditis (a form of auto-immune distinct from both Hashimoto’s disease and Graves’ disease).

Detailed explanation-2: -Background: Intrathyroid lymphoid tissue is accrued in Hashimoto thyroiditis (HT). Histologically, this acquired lymphoid tissue bears a close resemblance to mucosa-associated lymphoid tissue (MALT) and can evolve to lymphoma.

There is 1 question to complete.