ABDOMINAL
GENERALISED LYMPHADENOPATHY
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Question
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A histological study of the enlarged cervical lymph nodes revealed nodules with giant, spherical-oval form cells. These cells had a light pink cytoplasm and nuclei located on a periphery. The found out changes are characteristic for:
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Tuberculosis
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Lymphogranulomatosis (Hodgkin’s disease)
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Sarcoidosis (Boeck’s disease)
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Brucellosis
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Explanation:
Detailed explanation-1: -Classically, TB LD has been described as multiple, matted, hard to fluctuant with draining sinuses. But in stages 1 and 2, lymph nodes may be discrete, firm, and rubbery just like FL LD (19). Commonly involved lymph node regions in both (2, 7, 16, 17, 20, 21): cervical, axillary, and inguinal lymph nodes.
Detailed explanation-2: -Tuberculous lymphadenitis is a chronic, specific granulomatous inflammation of the lymph node with caseation necrosis, caused by infection with Mycobacterium tuberculosis or related bacteria. The characteristic morphological element is the tuberculous granuloma (caseating tubercule).
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