MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A microscopical investigation of a liver biopsy revealed a dystrophy, necroses of hepatocytes, a sclerosis, accompanied with destruction of a hepatic beam and a lobular structure, a formation of false lobes and regenerative nodes. What is the most likely diagnosis?
A
Cirrhosis of liver
B
Chronic gepatoz
C
Chronic hepatitis
D
Massive diffuse necrosis of liver
Explanation: 

Detailed explanation-1: -Alcoholic hepatitis is an acute inflammation of the liver. There is death of liver cells, often followed by permanent scarring. Alcoholic cirrhosis. Alcoholic cirrhosis is the destruction of normal liver tissue.

Detailed explanation-2: -Damaged hepatocytes release reactive oxygen species (ROS) and fibrogenic mediators, induce activation of HSCs, and stimulate the fibrogenic actions of myofibroblasts[59]. Apoptosis of hepatocytes is a common event in liver injury and contributes to tissue inflammation, fibrogenesis, and development of cirrhosis.

Detailed explanation-3: -In cases of hepatitis C, hepatitis B, autoimmune hepatitis, primary biliary cirrhosis, and steatohepatitis, piecemeal necrosis was found.

There is 1 question to complete.