MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A morphological investigation of a thyroid removed due to thyrotoxicosis struma revealed a diffuse infiltration of a gland by lymphocytes with a destruction of parenchyma and an area of connective tissue. What is the most likely diagnose?
A
* Hashimoto’s thyreoiditis
B
Anaphylactic reaction
C
Thyrotoxicosis
D
Cancer of thyroid
Explanation: 

Detailed explanation-1: -Chronic lymphocytic thyroiditis (CLT) is an autoimmune disease characterized by widespread lymphocytic infiltration, fibrosis, and late-stage parenchymal atrophy of thyroid tissue. It is the most common inflammatory disorder of the thyroid gland [3].

Detailed explanation-2: -The classic features of thyrotoxicosis are nervousness, diminished sleep, tremulousness, tachycardia, increased appetite, weight loss, and increased perspiration and signs are goiter, occasionally with exophthalmos, and rarely with pretibial myxedema.

Detailed explanation-3: -Hashimoto’s Thyroiditis, also known as Hashimoto’s disease, is an autoimmune disease that causes the body’s immune system to produce antibodies that attack thyroid tissue and damage the gland, leading to an under-productive thyroid.

There is 1 question to complete.