A post-mortem of a 25-year old woman who died from chronic kidney failure revealed a reddish malar rash (butterfly rash) and small (up to 0, 2 cm) pale tan spreading vegetations over the mitral valve surface. Histological investigation of kidneys showed foci of fibrinoid necrosis, eosinophilic deposits (hematoxylin bodies), wire loop lesions in the basement membrane of the glomerular tuft and karyorrhexis. What is the most likely diagnosis?

GENERALISED LYMPHADENOPATHY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A post-mortem of a 25-year old woman who died from chronic kidney failure revealed a reddish malar rash (’butterfly rash’) and small (up to 0, 2 cm) pale tan spreading vegetations over the mitral valve surface. Histological investigation of kidneys showed foci of fibrinoid necrosis, eosinophilic deposits (hematoxylin bodies), “wire loop” lesions in the basement membrane of the glomerular tuft and karyorrhexis. What is the most likely diagnosis?

A	Lupus erythematosus.
B	Nodular periarteritis.
C	Rheumatism.
D	Rheumatic arthritis.

Explanation:

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MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY