A renal puncture biopsy was taken from a patient with elevated blood sugar levels and high amounts of glucose in his urine. Histological investigation revealed extension of mesangium with focal accumulation of membranous substances and periglomerular sclerosis of some glomerules. In addition, there were found a hyalinosis and plasmatic infiltration of arterioles; lymphocytes, histiocytes and some leucocytes infiltration of a stroma; glycogen deposits within nephrocytes of narrow segment. What is the most likely diagnosis?

GENERALISED LYMPHADENOPATHY

Please wait while the activity loads.
If this activity does not load, try refreshing your browser. Also, this page requires javascript. Please visit using a browser with javascript enabled.

If loading fails, click here to try again

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A	Diabetic glomerulonephritis
B	Arteriolosclerotic nephrocirrosis
C	Pyelonephritis
D	Acute glomerulonephritis

Explanation:

Detailed explanation-1: -Despite advances in non-invasive biochemical and imaging investigations, kidney biopsies play a pivotal role in the diagnosis of kidney disease. They provide prognostic information that may result in treatment modification in up to 74% of patients.

Detailed explanation-2: -Bleeding-Bleeding is the most common complication of kidney biopsy. Many people may notice blood in their urine for several days after a kidney biopsy. More severe bleeding occurring around the kidney or into the urine is uncommon, but if it occurs, you may need a blood transfusion.

Detailed explanation-3: -A kidney biopsy is a procedure to remove a small piece of kidney tissue that can be examined under a microscope for signs of damage or disease. Your doctor may recommend a kidney biopsy-also called renal biopsy-to diagnose a suspected kidney problem.

There is 1 question to complete.

MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY