MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
An autopsy of a 42-year-old man revealed in the second segment of the right lung the focus of consolidation, 5 cm in diameter, surrounded with a thin capsule. The centre was presented by a dense dry crumbling tissue with a dim surface. Morphological changes in a lung are characteristic for:
A
Tuberculoma
B
Carcinoma of lung
C
Chondromas
D
The tumorous formof a silicosis
Explanation: 

Detailed explanation-1: -Tuberculous lymphadenitis is a chronic, specific granulomatous inflammation of the lymph node with caseation necrosis, caused by infection with Mycobacterium tuberculosis or related bacteria. The characteristic morphological element is the tuberculous granuloma (caseating tubercule).

Detailed explanation-2: -Typical CT findings of reactivation of pulmonary TB include centrilobular small nodules, branching linear opacities, patchy consolidation, and cavitation (19–21). Post-primary TB most commonly involves the upper lobes and the superior segments of the lower lobes (25, 26).

Detailed explanation-3: -In differential diagnosis of CTL, other granulomatous lymphadenitis should be considered such as non-tuberculous mycobacteria (including M. scrofulaceum, M. avium, and M. haemophilum), sarcoidosis, toxoplasmosis, tularemia, fungal disease, cat-scratch disease and neoplasms [7, 8].

Detailed explanation-4: -The symptomatology is acute with fever and painful, erythematous lumps over the neck. Tuberculous cervical lymphadenitis (also known as scrofula) is caused by Mycobacterium tuberculosis and presents with malaise, weight loss, and nontender neck lumps.

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