At the patient operated concerning a widespread tumour of an abdominal cavity, the considerable bleeding and declining of arterial pressure took place. After operation the acute renal insufficiency, resulted in the patients death, developed. An autopsy revealed the wide light pink cortical layer, which was clearly delimited from dark red pyramids. Histological investigation showed the absence of nuclei in epithelium of convoluted tubules, tubulorrhexis, venous hyperemia. Nuclei of the cells of vascular glomeruli and straight tubules were unchanged. What pathology of kidneys has developed at the patient?

GENERALISED LYMPHADENOPATHY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

At the patient operated concerning a widespread tumour of an abdominal cavity, the considerable bleeding and declining of arterial pressure took place. After operation the acute renal insufficiency, resulted in the patient’s death, developed. An autopsy revealed the wide light pink cortical layer, which was clearly delimited from dark red pyramids. Histological investigation showed the absence of nuclei in epithelium of convoluted tubules, tubulorrhexis, venous hyperemia. Nuclei of the cells of vascular glomeruli and straight tubules were unchanged. What pathology of kidneys has developed at the patient?

A	Necronephrosis
B	Infarct
C	Glomerulonephritis
D	Pyelonephritis

Explanation:

Detailed explanation-1: -Renal cortical necrosis is a severe and often irreversible form of acute tubular necrosis that is associated with septic abortion and placental abruption. Septic abortion is an infection of the uterus and the surrounding tissues, most commonly following nonsterile illicit abortions.

Detailed explanation-2: -Renal cortical necrosis (RCN) is characterized by patchy or diffuse ischemic destruction of all the elements of renal cortex resulting from significantly diminished renal arterial perfusion due to vascular spasm and microvascular injury.

Detailed explanation-3: -Usually the cause is a major, catastrophic disorder that decreases blood pressure. Symptoms may include dark urine, decreased urine volume, fever, and pain in the side of the body. Sometimes an imaging test or tissue analysis (biopsy) is done to confirm the diagnosis.

There is 1 question to complete.

MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY