ABDOMINAL
GENERALISED LYMPHADENOPATHY
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Question
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Histological investigation of a kidney biopsy showed sclerosis, lymphocyte-plasmocyte infiltration of the renal pelvis walls and calyces; tubules dystrophy and atrophy. The intact tubules were dilated, stretched by colloid-like masses. The epithelium was flattened. In whole, the microscopic picture of tissue sample had ‘a thyroid kidney’ pattern. What diagnosis is most probable?
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Chronic pyelonephritis
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Sharp pyelonephritis
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Glomerulonephritis
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Nephrosclerosis
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Explanation:
Detailed explanation-1: -The renal corpuscle consists of several histological structures (FIG 1): Glomerulus capillaries form a central tuft of looped capillaries located in the center of the renal corpuscle. These capillaries deliver blood and create a large surface area for renal filtration. These capillaries are optimized for filtration.
Detailed explanation-2: -A kidney biopsy is done to determine the etiology of the glomerulonephritis (GN) and the severity of the lesion, to identify whether other lesions, related to or not related to the GN, are present on the kidney biopsy and finally to ascertain the extent of chronicity of the GN.
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