MRCP UK EXAMINATIONS

ABDOMINAL

GENERALISED LYMPHADENOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
hypersensitivity reaction
A
when the body is exposed to a foreign substance and the immune system overreacts and harms the body
B
inflammation of the lymph nodes
C
enlargement of the spleen
D
None of the above
Explanation: 

Detailed explanation-1: -Allergic reactions begin in your immune system. When a harmless substance such as dust, mold, or pollen is encountered by a person who is allergic to that substance, the immune system may over react by producing antibodies that “attack” the allergen.

Detailed explanation-2: -There are four types of hypersensitivity reactions: type I is immunoglobulin E, or IgE mediated; type II is mediated by antibodies that activate cellular cytotoxicity, type III is mediated by immune-complexes, and type IV is a delayed T cell mediated hypersensitivity reaction.

Detailed explanation-3: -Type II hypersensitivity reaction refers to an antibody-mediated immune reaction in which antibodies (IgG or IgM) are directed against cellular or extracellular matrix antigens, resulting in cellular destruction, functional loss, or tissue damage.

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