MRCP UK EXAMINATIONS

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ABDOMINAL

GENERALISED LYMPHADENOPATHY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The biopsy is taken from a suspicious site at the mucous the right bronchus of a 58-year old male, with a history of the chronic bronchitis, pneumosclerosis and cardiopulrnonary insufficiency. Flistological investigation revealed cellular and tissue atypia, presence of a “cancer pearls” structures. What pathological process associated with histological changes listed below?
A
Squamous cell keratinous carcinoma
B
Chronic polypous bronchitis
C
Bronchiectasis
D
Squamous metaplasia of the bronchial epithelium
Explanation: 

Detailed explanation-1: -Bronchitis is an inflammation of the lining of your bronchial tubes, which carry air to and from your lungs. People who have bronchitis often cough up thickened mucus, which can be discolored. Bronchitis may be either acute or chronic.

Detailed explanation-2: -Pathophysiology. Chronic bronchitis is thought to be caused by overproduction and hypersecretion of mucus by goblet cells. Epithelial cells lining the airway response to toxic, infectious stimuli by releasing inflammatory mediators and eg pro-inflammatory cytokines.

Detailed explanation-3: -Frequent coughing or a cough that produces a lot mucus. Wheezing. A whistling or squeaky sound when you breathe. Shortness of breath, especially with physical activity. Tightness in your chest. 16-Jun-2021

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