ABDOMINAL
GENERALISED LYMPHADENOPATHY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The patient treated for a cold by the big doses of paracetamol, presented symptoms of an oliguria and a/otemia. In 5 days he died of an acute renal insufficiency. Histological investigation of kidneys revealed the diffusive edema of an interstitial tissue of a kidneys cortex, its infiltration by lymphocytes, the eosinophils, some neutrophils. Almost intact glomerules were found along with a destruction of a tubular epithelium. Name the most probable type of a kidneys lesion?
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Tubulointerstitial nephritis
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Acute glomerulonephritis
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Nephrotic syndrome
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Pyelonephritis
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Explanation:
Detailed explanation-1: -The pathophysiology of renal toxicity in acetaminophen poisoning has been attributed to cytochrome P-450 mixed function oxidase isoenzymes present in the kidney, although other mechanisms have been elucidated, including the role of prostaglandin synthetase and N-deacetylase enzymes.
Detailed explanation-2: -Control your blood pressure. Meet your blood glucose goal if you have diabetes. Work with your health care team to monitor your kidney health. Take medicines as prescribed. Work with a dietitian to develop a meal plan. Make physical activity part of your routine. Aim for a healthy weight. More items
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