MRCP UK EXAMINATIONS

ABDOMINAL

RENAL REPLACEMENT THERAPY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In the collecting duct, what is reabsorbed in the presence of ADH?
A
Ions like Na+ and Cl-
B
Nutrients like glucose and amino acids
C
Substances like drug metabolites and waste
D
Water
Explanation: 

Detailed explanation-1: -Final answer: Proximal convoluted tubule is involved in reabsorption of water even in presence of hormone ADH (Anti-diuretic hormone).

Detailed explanation-2: -Explanation: ADH acts upon the collecting ducts and distal convoluted tubules of nephrons to increase water reabsorption. It causes an increase in the number of aquaporins in order to allow for this.

Detailed explanation-3: -ADH primarily affects the ability of the kidney to reabsorb water; when present, ADH induces expression of water transport proteins in the late distal tubule and collecting duct to increase water reabsorption.

Detailed explanation-4: -After entering the duct cell from the collecting duct lumen through the AQP2 channels, the water exits the cell through the AQP3 and AQP4 channels located in the cell basolateral membrane, causing the water to enter the interstitial space of the nephron.

Detailed explanation-5: -ADH-Antidiuretic hormone is also known as Vasopressin. Vasopressin helps in the reabsorption of the water from the urine in the kidney.

There is 1 question to complete.