ABDOMINAL
RENAL REPLACEMENT THERAPY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Ions like Na+ and Cl-
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Nutrients like glucose and amino acids
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Substances like drug metabolites and waste
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Water
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Detailed explanation-1: -The main role of the collecting duct is the reabsorption of water, through the action of anti-diuretic hormone (ADH) and aquaporins. ADH is produced in the hypothalamus, and stored in the posterior pituitary gland until it is released.
Detailed explanation-2: -Water reabsorption takes place in the cortical collecting duct (CCD) cells, induced by the peptide hormone vasopressin. An increase in 3’5’-cyclic adenosine monophosphate (cAMP) levels in these cells leads to an increasing permeability of the CCD apical membrane to water.
Detailed explanation-3: -Glucose, amino acids, NaCl and other essential salts are reabsorbed in the second step of urine formation i.e Tubular Reabsorption.
Detailed explanation-4: -As the collecting duct descends through the medulla, the increasing osmolarity in the surrounding interstitial fluid drives water reabsorption.