MRCP UK EXAMINATIONS

ABDOMINAL

RENAL REPLACEMENT THERAPY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
NaCl is isotonic to red blood cells. Which of these describes what will happen if a technician misplaces a decimal point and makes 9.0% NaCl solution instead and administers it to a patient?
A
The cells exposed to the solution will burst.
B
The cells exposed to the solution will shrink.
C
The cells will remain the same size.
D
The cells exposed to the solution will expand but not burst.
Explanation: 

Detailed explanation-1: -0.9% NaCl is isotonic to red blood cells. Which of these describes what will happen if a technician misplaces a decimal point and makes 9.0% NaCl solution instead and administers it to a patient? The cells exposed to the solution will shrink.

Detailed explanation-2: -When a red blood cell is placed in an isotonic solution, there will be no net movement of water. Both the concentration of solute and water are equal both intracellularly and extracellularly; therefore, there will be no net movement of water towards the solution or the cell.

Detailed explanation-3: -If a red blood cell (intracellular concentration of 0.9% salt) is placed into a test tube containing 10% salt solution, what would happen to it? It would fill with water and burst. No worries! We’ve got your back.

Detailed explanation-4: -The red blood cell has its normal volume in isotonic NaCl. Erythrocytes remain intact in NaCl 0.9%, resulting in an opaque suspension.

Detailed explanation-5: -The effects of hypertonic NaCl. The red blood cells, therefore, lose their normal biconcave shape and shrink or crenate.

There is 1 question to complete.