ABDOMINAL
THALASSEMIA
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Clinical signs of disease vary, depending on the class of ____ involved, as well as gene zygosity.
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Altered stability
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globin chain
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Solubility
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Altered function
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Explanation:
Detailed explanation-1: -Thalassemia can be defined as a condition in which a reduced rate of synthesis of one or more of the globin chains leads to imbalanced globin-chain synthesis, defective hemoglobin production, and damage to the red cells or their precursors from the effects of the globin subunits that are produced in relative excess.
Detailed explanation-2: -Thalassemia is a genetic disorder in which there is decreased production of one of the globin chains found in hemoglobin. This oxygen-transporting molecule in blood normally contains four globin chains, two alpha (a) and two non-a, each with its own heme group (made of an iron atom bound in protoporphyrin ring).
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