MRCP UK EXAMINATIONS

ABDOMINAL

THALASSEMIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
couple come to consult about thalassemia anemia Wife was pregnant at 8 weeks, husband:Hb 11.7%, Hct 35.6%, MCV 67.7 fl, RDW 15.3%OF +ve, DCIP-veHb typing:HbA 87.8%, HbA2 2.9%, HbF 0.3%Inclusion body-negativeResult
A
All children will be thalassemia carriers.
B
75% of children are asymptomatic.
C
50% of children have mild thalassemia.
D
It is advisable to screen for the risk of thalassemia in children.
Explanation: 

Detailed explanation-1: -If you have thalassemia and become pregnant, you will need to see your healthcare provider for checkups frequently-each month for the first two trimesters (28 weeks) and then every 2 weeks toward the end of your pregnancy. Your provider may want to run more tests to check your heart, liver, or thyroid function.

Detailed explanation-2: -Many times people with thalassemia are prescribed a supplemental B vitamin, known as folic acid, to help treat anemia. Folic acid can help red blood cells develop. Treatment with folic acid is usually done in addition to other therapies.

Detailed explanation-3: -The MCV is usually less than 75 fl with thalassemia and rarely less than 80 fl in iron deficiency until the hematocrit is less than 30 percent. For children, the Mentzer index (MCV/red blood cell count) can help distinguish between iron deficiency and thalassemia.

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