ABDOMINAL
THALASSEMIA
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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True
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False
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Either A or B
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None of the above
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Detailed explanation-1: -Background. Hemoglobin Constant Spring (Hb CS) is an abnormal Hb caused by a mutation at the termination codon of 2-globin gene found commonly among Southeast Asian and Chinese people. Association of Hb CS with °-thalassemia leads to a thalassemia intermedia syndrome commonly encountered in the region.
Detailed explanation-2: -Patients with thalassemia do not produce enough hemoglobin (Hb) A (22) because their cells cannot manufacture either the alpha or beta polypeptide chain of human hemoglobin. Alpha-thalassemia depresses only the production of the alpha chains, and beta-thalassemia depresses only the production of the beta chains.
Detailed explanation-3: -What is Thalassemia? Thalassemia is an inherited (i.e., passed from parents to children through genes) blood disorder caused when the body doesn’t make enough of a protein called hemoglobin, an important part of red blood cells.