History of Sickle Cell continued All four patients were of African descent-led to common 1949 ..... named SCD as the first molecular disease First proof of disease caused by an protein First disease understood on the 1957-amino acid change in beta globin chains identified

THALASSEMIA

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

History of Sickle Cell continued All four patients were of African descent-led to common 1949 ____ named SCD as the first “molecular disease” First proof of disease caused by an protein First disease understood on the 1957-amino acid change in beta globin chains identified

A	misconception
B	Linus Pauling
C	abnormal
D	molecular level
E	single

Explanation:

Detailed explanation-1: -So why are African Americans Affected More? SCD and SCT impact African Americans at disproportionate rates. This is simply because they both are evolutionary traits that individuals develop in response to help protect them from malaria. Around 50% of the global population live in areas where malaria exists.

Detailed explanation-2: -Notably, sickle cell anemia was the first genetic disease to be examined at the molecular level. The first documented case of sickle cell anemia was published in 1910 by a physician named James Herrick. He described a 20 year old college student who was severely anemic.

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MRCP UK EXAMINATIONS

ABDOMINAL

THALASSEMIA