MRCP UK EXAMINATIONS

ABDOMINAL

THALASSEMIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Luspatercept mechanism of action (class):
A
Erythroid maturation agent:restores RBC production
B
Epoetin alfa analogue
C
Multivitamin with iron
D
Heavy metal antagonists:Iron-binding agent
Explanation: 

Detailed explanation-1: -Luspatercept is a medication used to manage and treat anemia in myelodysplastic syndromes, primary myelofibrosis, and beta-thalassemia. It is a recombinant fusion protein that binds transforming growth factor-beta ligands to reduce SMAD2 and SMAD3 signaling.

Detailed explanation-2: -Drug Type: Luspatercept is a recombinant fusion protein. This medication is classified as a hematopoiesis agent (for more detail, see “How Luspatercept Works” below).

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