MRCP UK EXAMINATIONS

ABDOMINAL

THALASSEMIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
SICKLE CELL ANEMIA Greatest prevalence in (but also seen in other areas where is endemic) babies born/year in Africa  2, 600/year in and /year in Europe Relationship to Plasmodium falciparum and other forms of malaria
A
sub-Saharan Africa
B
malaria
C
 250, 000
D
U.S.
E
 1, 300
F
G
sub-terrania Africa
H
Middle East
Explanation: 

Detailed explanation-1: -It turns out that, in these areas, HbS carriers have been naturally selected, because the trait confers some resistance to malaria. Their red blood cells, containing some abnormal hemoglobin, tend to sickle when they are infected by the malaria parasite.

Detailed explanation-2: -However, about 300, 000 babies are born every year with sickle cell anemia. Most of these cases occur in Nigeria, the Democratic Republic of the Congo, and India. Experts predict this number will pass 400, 000 by 2050.

Detailed explanation-3: -Sickle cell disease (SCD) is common throughout much of sub-Saharan Africa, affecting up to 3% of births in some parts of the continent.

There is 1 question to complete.