ABDOMINAL
THALASSEMIA
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What is the percentage for Thalassemia patients to get a donor sibling match?
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15%
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20%
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25%
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50%
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Explanation:
Detailed explanation-1: -As complicated as this procedure sounds the thalassemia-free overall survival rate of an HLA-matched sibling stem cell transplantation patient is 85% to 90% which is significant.
Detailed explanation-2: -Matching for the HLA-A, -B, -C, -DRB1 and-DQB1 loci is referred to as a 10/10 match, when HLA-DPB1 is included it becomes a 12/12 match. Matching for HLA-A, -B, -C, and-DRB1 loci is an 8/8 match. There is still no international standard for reporting DRB3/4/5 as well as DQA1 and DPA1 mismatches.
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