ABDOMINAL
THALASSEMIA
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following alpha thalassemia is inconsistent with life?
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Alpha thal trait
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Alpha thal minor
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Hgb H
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Hgb Bart’s
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Explanation:
Detailed explanation-1: -Hemoglobin Bart’s is a common hemoglobin variant that is only detectable during the newborn period. Its presence indicates that one or more of the infant’s four alpha globin genes are dysfunctional, which results in alpha thalassemia.
Detailed explanation-2: -Alpha thalassemia trait (Alpha thalassemia 1) results from loss of two genes and causes a mild microcytic anemia which may resemble iron deficiency anemia. The loss of three genes causes hemoglobin H diseases which is a moderately severe form of thalassemia.
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