MRCP UK EXAMINATIONS

ABDOMINAL

THALASSEMIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following lab results would be expected in a patient with alpha thalassemia?
A
MCH = 32 pg
B
MCV = 70 fl
C
stomatocytes
D
Increased Hgb A
Explanation: 

Detailed explanation-1: -MCV/RBC values of less than 11.5 suggest thalassemia trait, while values greater than 13.5 suggest iron deficiency anemia. A much more definitive measurement of iron deficiency is to determine the ferritin level.

Detailed explanation-2: -The blood count in -thalassemia carriers shows low mean corpuscular volume (MCV) and low mean corpuscular hemoglobin (MCH). These parameters, which are easily measured by automated blood cell counters, can indicate suspicion of a carrier state.

Detailed explanation-3: -°-trait is usually marked by slight anemia, slightly reduced MCV and MCH, RBC microcytosis, hypochromia, and anisopoikilocytosis. During the neonatal period, Hb Bart’s can be detected in moderate amounts (3–8%). Some Heinz inclusion bodies (intracellular Hb precipitates) may also be detected.

There is 1 question to complete.