ABDOMINAL
THALASSEMIA
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which thalassemiapresents with an abnormal hgb that precipitates in red cells and will have a golf ball appearance after incubation with brilliant cresyl blue
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Hgb F
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Hgb H
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Hgb Bart’s
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Beta thal major
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Explanation:
Detailed explanation-1: -Heinz bodies are denatured haemoglobin (seen in oxidant injury, G6PD deficiency). Haemoglobin H inclusions are seen in alpha-thalassemias giving rise to the characteristic ‘golf ball’ appearance of the erythrocytes.
Detailed explanation-2: -In people with the characteristic features of alpha thalassemia, a reduction in the amount of hemoglobin prevents enough oxygen from reaching the body’s tissues. Affected individuals also have a shortage of red blood cells (anemia ), which can cause pale skin, weakness, fatigue, and more serious complications.
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