MRCP UK EXAMINATIONS

CLINICAL ENCOUNTERS

ANKYLOSING SPONDYLITIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Tricyclic antidepressant and muscle relaxant AMT à Improve sleep, ↓ active. peny, ES min NSAIDs. Firstline therapy Indomethacin Is this statement correct?
A
Correct
B
Salah
C
Can be both
D
None of the above
Explanation: 

Detailed explanation-1: -Doxepin (Silenor) is used to treat insomnia (difficulty falling asleep or staying asleep) in people who have trouble staying asleep. Doxepin (Silenor) is in a class of medications called tricyclic antidepressants. It works by slowing activity in the brain to allow sleep.

Detailed explanation-2: -TRICYCLIC ANTIDEPRESSANTS. Sedating tricyclic antidepressants (TCAs) are widely used for their sleep-promoting effects. They may serve as alternatives to benzodiazepine receptor agonists when used at relatively lower than antidepressant doses. Unlike benzodiazepines, TCAs are not known to suppress deep sleep.

Detailed explanation-3: -Tricyclic antidepressants are a class of medications used in the management and treatment of major depressive disorder.

Detailed explanation-4: -Tricyclic antidepressants (also called tricyclics or TCAs) are named for their chemical structure (3 rings). They are among the earliest antidepressants developed and first came into widespread use in the 1950s. Some of the available tricyclics include imipramine, amitriptyline, clomipramine and nortriptyline.

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