CLINICAL ENCOUNTERS
ANTICOAGULATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Iron chelaters or non ion chelators
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Calcium chelaters and Non calcium chelaters
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Either A or B
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None of the above
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Detailed explanation-1: -Citrate, which chelates positively charged calcium ions and thereby blocks calcium-dependent clotting factor reactions, is the anticoagulant typically used for collection of blood for transfusion as well as for in vitro evaluation of platelet function.
Detailed explanation-2: -Sodium Citrate: This is most commonly used anticoagulant, mainly used to prepare citrated plasma for the evaluation of coagulation disorders as it is not inhibitory to calcium ions.
Detailed explanation-3: -Potassium Oxalate This may be sodium, potassium, ammonium, or lithium oxalic acid salt used as an anticoagulant. This forms an insoluble complex with calcium ions (precipitate with calcium as a salt).
Detailed explanation-4: -rivaroxaban (Xarelto) dabigatran (Pradaxa) apixaban (Eliquis) edoxaban (Lixiana)